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In the vast landscape of chemical manufacturing, few names resonate with the same level of innovation and quality as Sachtleben. Known for their meticulous approach to production, Sachtleben has established itself as a leading titanium dioxide (TiO2) manufacturer under its TIO2 brand. Titanium dioxide, often recognized for its superior pigmenting properties, is widely used in industries ranging from paints and coatings to plastics and paper.

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  • In a study published in the journal Food and Chemical Toxicology in 2016, researchers investigated whether titanium dioxide exposure led to an increase in colorectal tumor creation in mice by using a colitis associated cancer model. By measuring tumor progression markers, the researchers found that mice given titanium dioxide experienced enhanced tumor formation in the distal colon.  There was also a decrease of cells that act as a protective barrier in the colon. The researchers wrote: “These results suggest that E171 could worsen pre-existent intestinal diseases.”